Millions across the central and eastern United States are bracing for a prolonged and dangerous heatwave this week, with temperatures set to soar ahead of the Fourth of July holiday.

The National Weather Service has warned that high humidity will make conditions feel even more oppressive.

On Sunday, parts of the US, including Phoenix and central Texas, along with much of the Southwest, already saw temperatures around 38C (100F).

Concurrently, severe wildfire conditions are developing across the West, with new blazes emerging.

More than 130 million Americans in southern and Great Plains states were under moderate to severe heat risk over the weekend, a figure expected to grow as the week progresses and temperatures intensify.

Forecasters predict several consecutive days of temperatures exceeding 38C (100F) will engulf the lower Great Lakes, mid-Atlantic, and the Mississippi and Ohio River valleys.

Record highs could be established in parts of the lower Great Lakes, mid-Atlantic, and New England later in the week, according to Bryan Putnam, a weather service meteorologist.

Major cities hosting World Cup matches and celebrations for America’s 250th anniversary could experience their highest temperatures of the year to date.

Feeling the heat will be the East Coast cities of New York, Philadelphia, Washington and Baltimore, and Midwestern and Great Lakes cities including Chicago, Indianapolis, St. Louis and Detroit. Southern cities including Dallas, Little Rock, Arkansas, and Memphis, Tennessee, will also see high temperatures.

High heat will last into next weekend across the Great Plains, the Southeast and the mid-Atlantic, the weather service said.

Temperatures will reach well into the 90s and low 100 degrees Fahrenheit (mid to high 30s Celsius), the weather service said. High humidity will lead to heat indexes of 100 to 110 degrees F (40 C to 43 C), and as high as 115 F (46 C).

“That’s heat that’s impactful to anyone,” Putnam said. “It’s not just older adults or younger children or people who are spending a ton of time outdoors, maybe straining themselves a little more than normal. This is heat that really could impact everyone, especially with people outdoors going into the holiday weekend.”

The heat index, which factors in humidity and is included on many weather forecasts, provides a sense of how hot it really feels — and what’s dangerous for prolonged exposure or strenuous activity.

AccuWeather meteorologist Tyler Roys said temperatures will be significantly above normal. For instance, in Washington, highs around July Fourth average around 89 degrees F (32 C), while Indianapolis averages around 85 degrees F (29 C). But this week, both cities will be hotter by 10 or 11 degrees F, Roys said.

The high pressure system — an area of dry, sinking air — creating the heat will act like a “rock” that will force storms to go around it and limit rainfall across the East, Roys said. That’s sometimes called a “heat dome.”

Nightly lows in the 70s F (21 to 26 C) or even high 80s won’t provide much relief, meteorologists said.

For those who don’t have air conditioning, especially in Eastern Seaboard cities like New York where lows may not dip below 80 F (27 C), it’s going be miserable to sleep, Roys said.

Roys also said this is a primetime for heat-related illnesses because people’s bodies aren’t able to recover and cool off.

During extreme temperatures, limit outdoor activity, stay hydrated and ensure access to air-conditioning and other cooling areas, the weather service said.

The weather service said it expected extremely dry and windy conditions that could promote rapid wildfire spread across the Great Basin and the Southwest on Sunday.

In hot, windy conditions near the Colorado-Utah border, three firefighters working for the U.S. Wildland Fire Service and U.S. Forest Service were killed, and two others sustained burn injuries, when they were overcome by flames from fast-moving wildfires.

Wildfire activity has intensified across the Western U.S. as hot, dry and windy weather fueled flames in Utah, Colorado, Arizona and elsewhere.