The pontiff’s first Latin America trip will take him back to Peru, where he spent decades as a missionary and bishop.

Pope Leo XIV will return to the region that shaped much of his ministry, making his first trip to Latin America as head of the Catholic Church in November.

The Vatican announced on Wednesday that Leo will travel to the three South American countries — Uruguay, Argentina and Peru — from November 6 to 17.

Pope Leo’s stop in Peru is especially significant. He spent decades, on and off, in the Andean country, first as a missionary and later as a bishop for the Diocese of Chiclayo in northern Peru.

The trip will also mark the first papal visit to Argentina and Uruguay in nearly 40 years.

The itinerary includes stops in the cities of Montevideo, Paysandu and Florida in Uruguay from November 6 to 8; Buenos Aires, Cordoba and Lujan in Argentina from November 8 to 11; and Lima, Chiclayo, Cusco and Pucallpa in Peru from November 11 to 17. More details about the pope’s itinerary will be released closer to the trip.

Pope Leo’s return to Chiclayo is likely to be one of the most emotional moments of the tour.

Although born in Chicago, Pope Leo first arrived in Peru in 1985 at age 30. Over the next three decades, he moved between the United States and Peru as a missionary.

In 2014, Pope Francis appointed him to the Diocese of Chiclayo. He became a Peruvian citizen the following year and led the diocese until 2023.

Upon his election as pope in 2025, he thanked the diocese in his inaugural address — and the city embraced him as the first “papa chiclayano”, the first pope from Chiclayo. Thousands of people gathered in Chiclayo’s main square to celebrate the results of the papal conclave.

The Argentina leg of the visit is also heavily symbolic. Leo’s predecessor, Pope Francis, was born in Argentina but never returned to his home country during his 12-year papacy, despite repeated invitations from multiple presidents.

Pope Francis made his final trip to South America in 2018, when he visited Peru and Chile. Pope Leo will become the first pope to visit Argentina since John Paul II travelled there in 1987.

Latin America and the Caribbean are considered the regions with the largest Catholic populations.

In a survey of religious distribution in 2013, the Pew Research Center indicated that 39 percent of the world’s Catholics were located in Latin America and the Caribbean, compared to 24 percent in Europe, the next largest region.

But the Catholic Church is grappling with declining influence across Latin America. Polling by the public opinion firm Latinobarometro found the share of people in the region who identify as Catholic fell from about 80 percent in 1995 to 54 percent in 2024. Evangelical Christianity, meanwhile, has seen its influence grow in the region.

Since assuming the papacy, Pope Leo has ramped up his international travel schedule.

Before heading to South America, he is due to visit France from September 25 to 28, his first trip to the country as pope, and he visited four African countries, as well as Spain, earlier this year.