The US has imposed a new round of sanctions on Cuban officials and companies, Secretary of State Marco Rubio says.

Nine state-owned mining, metal and building firms, the Ministry of Construction and officials connected to a Cuban-based international institute have been named in the latest tranche of economic sanctions.

In a statement, Rubio accused various figures of “ferrying a new brigade of international sympathizers to Havana to network with regime officials” to coincide with the late former leader Fidel Castro’s 100th birthday.

Cuba has denounced all sanctions imposed by the Trump administration.

Rubio said the figures targeted by the sanctions form “part of the regime’s raison d’être of exporting Marxism, racial resentment, and Communist violence across the world”.

Rubio continued: “Today’s designations make clear that the Trump Administration will not tolerate the Cuban regime’s efforts to fund its repression or continue its decades-long campaign of subversive anti-American activities.”

The leadership of the Cuban Institute of Friendship with the Peoples (ICAP) were targeted in the latest round of US sanctions.

Founded in 1960 by Castro, the ICAP has traditionally been used by the Cuban government to foster ties with like-minded organisations around the world by hosting visiting groups of activists who also promote pro-Cuban government campaigns in their own countries.

Rubio, however, accuses the group of “misleading and corrupting American citizens with lies, spy tradecraft and malfeasance”.

Among those to be targeted is the group’s president, Fernando Gonzalez Llort, a member of a spy ring called the Cuban 5, who were part of a prisoner exchange during the Obama-era thaw with Havana.

Havana’s senior figures across the energy, financial and defence sectors are already subject to US sanctions. The country’s tourism industry has also plummeted, a key source of income for the beleaguered government.

Cuban Foreign Minister Bruno Rodríguez condemned Rubio’s announcement, writing on X that he was trying to “punish” Cuban companies and further “harm” the economy.

Rodríguez added it would prevent the government “from guaranteeing basic services to the population, which are already in a critical situation as a result of the blockade”.

The US has imposed an effective oil blockade on Cuba since the beginning of the year. With the island’s aging electricity infrastructure heavily reliant on fuel imports, hospitals have resorted to using emergency generators.

Lengthy and frequent power cuts have triggered rare protests in Cuba, where public dissent is typically punished with long prison sentences.