May 4 (UPI) — U.S. Secretary of State Marco Rubio is scheduled to meet this week with Pope Leo XIV in Italy, with planned topics including the Middle East and Cuba.

The State Department announced Monday that Rubio will meet this week with Leo, and an official Vatican calendar notice confirmed the meeting will take place Thursday.

The Washington Post quoted the announcement as saying Rubio, a prominent Catholic in President Donald Trump’s administration, will “discuss the situation in the Middle East and mutual interests in the Western Hemisphere.”

A USA Today report indicated Rubio and Leo are also expected to discuss Cuba, which has been subject to a U.S. oil embargo and other measures in an attempt to force the smaller country into an economic deal.

The meeting will be the first time a high-ranking administration official has met with the pope since Trump took to social media last month to brand Leo “weak on crime” and “terrible for foreign policy.”

“He wasn’t on any list to be Pope, and was only put there by the Church because he was an American, and they thought that would be the best way to deal with President Donald J. Trump,” Trump wrote in April. “If I wasn’t in the White House, Leo wouldn’t be in the Vatican.”

Rubio and Vice President JD Vance previously met with Leo during a private audience at the Vatican in May 2025, one day after the pope’s Inauguration Mass.